- The heavy armor on the Tusk Thumper makes its body impervious to all forms of attack. To deal damage to it, players must destroy the destructible armor plates on the Thumper's knees, which will reveal a glowing bluish-green weak spot on each leg that can be attacked. Each weak spot constitutes a quarter of the Thumper's health, with each leg weak spot closing up if its health pool is depleted, thus all 4 leg weak spots must be destroyed in order to kill the Thumper.
- The Thumper possesses unusual agility for a unit of its size, capable of jumping high into the air to either reposition itself or attempt to slam down onto enemies beneath it. It is also capable of charging forward at great speeds, knocking over any enemies in its path.
- Occasionally, the Thumper will brace its legs and then use its pneumatic groundpounder on its belly, which it slams into the ground repeatedly to create up to 5 radial shockwaves that deal damage and knockback in a large area. The Thumper in this state is immobile, however, making it easier for players to aim for its weak spots, particularly its "back" two legs that it typically keeps turning away from you as it moves around and turns to aim weapons at you. These shockwaves, as the physics of their source imply, are purely through the ground. If you are hovering above the ground such as in an Archwing they will have no effect on you, although the sounds of the impacts will stagger your aim. This can be a key way of getting to the "back" weakspots.
- The Thumper has two ranged weapons consisting of a large telescopic cannon on its front and a rapid-fire autocannon on one side. These weapons have their own hitboxes and hitpoints, which can be destroyed to temporarily knock them out of commission.
- Dormant Thumpers are buried underground and thus are not visible from long distances. They will only emerge from the ground once players are within striking distance.
- When a Thumper only has half its health left, it will eject a hatch on its top side, opening up a launcher that will allow it to release Tusk Seeker Drones to call in reinforcements.
- The advanced Thumper variants - the Tusk Thumper Bull and Tusk Thumper Doma - have higher chances of spawning when performing high level Bounties.
- Only one Thumper at a time will appear on the Plains at any instance, and there is a 90 to 120 second cooldown time before another Thumper will spawn.
- Tusk Thumpers can drop most Plains of Eidolon-exclusive resources on death, including common and uncommon fish and animal parts, as well as common to uncommon ores and gems, but only the Bull and Doma variants drop Seram Beetle Shell, Sentirum and Nyth.
- can use for a chance to double the drops from the Thumper's corpse.
- Tusk Thumpers have set spawn locations but are randomly encountered only in the daytime. Only one Tusk Thumper can be present in any instance. The following map shows all the possible spawn locations:
- Decreasing Tusk Thumper movement speed, with 's , or 's can make it easier to shoot the weak spots.
- Zenurik's Temporal Blast also works on Tusk Thumper.
- 's or 's can be used to strip down Tusk Thumper's armor, thus making it take more damage. However, the following abilities do not work on the Thumper:
- Tusk Thumper's armor can be reduced using .
- Abilities that make Tenno invisible, e.g. 's , can help making Tusk Thumper less active. It will not retaliate against invisible Tenno and less likely move around.
- The Thumper is incapable of hitting with its melee, charge, and shockwave attacks if she is above the ground in her form. While it can still shoot her, it will prefer to attack her Razorflies, which can keep the Thumper busy while Titania shoots its weak spots.
- A beacon from 's alternate fire can be used to tag a weak spot, allowing Tenno to deal damage with ease.
- Operator's Void Beam can also deal significant damage against the Thumper, especially with Prism/Scaffold that has Punch Through and/or AoE damage.
- This method is quite ammo-efficient as Void Beam is simply rechargeable, while the Thumper requires a lot of ammo to bring down.
- The Sarpa built for Radiation damage deals more damage to the weakspots than most (perhaps all) other weapons.
- Stolen Tusk Dargyn can be used to slowly fight the Thumper as well. Though it is recommended to periodically destroy its gun to prevent retaliation as Dargyn is not so resilient.
- Necramechs trivialize the fight, as they are immune to the thumper's knockbacks, and their heavy weapon's ammo recharges. Combine this with a debuffing frame such as then take them down with the mech.
- Tusk Thumper is the first Grineer ground vehicle and second hostile ground vehicle introduced in the game, first being Coildrive.
- There are two inactive Tusk Thumpers of unknown variant in orange in a small base area at the middle point between Ostwan Range and Renthi Spring on Plains of Eidolon.
- There is a unique-looking console positioned close to each of them, presumably for maintenance purpose.
- Thumpers will despawn after a period of time. Even within view of the player.
- Thumpers can on very rare occasion spawn inside caves, unable to move around - Only turn. This seems to only happen if the player is inside said cave.