The targets are special version of the normal enemy which simaris will inform you if the target will spawn in that mission.

Simaris Synthesis Target

They will have blue outline and zooming in with simaris's scanner will mark them and show 4 scanning spots.

Simaris Synthesis Target - Completely scanned

Once you scanned all 4 spots, it'll go boom!

Simaris Synthesis Target - Captured

Dat standings!

edit: I've just noticed that when i zoom in with simaris's scanner, there will be some blue light thingy floating around. These lights are actually a path that lead me directly to the target.

So, yeah, we can just mindlessly follow them lights and not actually hunting anything.

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