She once worked as a field scientist on Earth, researching ways to restore the polluted planet to its former nature, but as an Infested biologist, she was transferred to work on the Warframe project on Lua, spearheaded by Executor Ballas, at some time during The Old War. Working with Archmedian Margulis, she helped with the development of Transference technology, the Somatic Links, that allowed Tenno to link their consciousness with Warframes, unlocking its full autonomy and control to fight against the Sentient threat.
At some point in the project, she was responsible for the development of the Titania Warframe, condemning herself for creating tools of war. Believing she has a chance to correct this wrong, she planned an escape back to Earth, hoarding Apothics and Somatic Links in hopes of restoring the forests and wildlife that once flourished the planet. She performed Transference with the trees themselves, transferring her consciousness in an effort to will the regrowth of Earth's forests.
The Orokin eventually found out about her defection and sent Dax soldiers to execute her, burning forests in an act of arson. Titania came to Silvana's rescue, sacrificed her life when killing the Dax that harmed her. Multiple millennia into the future, Knave, Orphid, and Feyarch Specters still protect the so-called Silver Grove where Silvana gave up her humanity to become one with nature.
- The Silver Grove, the quest she was introduced.