Unleashing an endless epidemic of contagious spores, the mistress of malady Saryn eradicates her foes through horrific decay. Erupt caustic pustules to spread her disease, shed deceptive husks to draw enemy fire, as she injects lethal venom and exhales deadly viruses to cleanse the System with her toxic touch. Saryn blossomed in Update 7.0 (2013-03-18).
Acquisition
Saryn's main blueprint can be purchased from the Market. Saryn's component blueprints are obtained from defeating Kela De Thaym on Merrow, Sedna.
Alternatively, upon completion of The Duviri Paradox, Saryn's main and component blueprints can be earned from The Circuit. By selecting her on the rotating week she is available, players can earn her blueprints after reaching Tier 2 (Neuroptics), 5 (Chassis), 8 (Systems), and 10 (Main) rewards.
After the poll on the founders forum she was to be named after Sarin, which is a colorless, odorless liquid, used as a chemical weapon owing to its extreme potency as a nerve agent. It was altered to Saryn when a first responder to a sarin attack suggested a name tweak, along with Sarin sounding too masculine.[1]
She is the first female Warframe whose base stats defy a trend of fragility, having health and armor values that exceed those of many male Warframes.
She is the 4th tallest out of the current 49 other frames, and is matched by Gyre in terms of height.
Saryn is the 1st Warframe to replace Alloy Plates with Circuits for construction – the 2nd is the Valkyr.
Saryn was given an Immortal Skin in Update 12.0 (2014-02-05).
Unlike most other Warframes, Saryn does not bear a symmetrical appearance. This is due to the tissue/matter which is situated on her right thigh, her neck and around her hips. This tissue/matter vaguely resembles the Infested tissue (or rather the structure of it) sometimes found on Corpus and Grineer ships.
Saryn's ability sound effects post Update 22.20 (2018-05-17) are voiced by [DE]Danielle.
Saryn’s Systems is a requisite ingredient for Chroma’s Systems.
Status Effects inflicted by Saryn's weapons and abilities last 25% longer.
Abilities
View Maximization ▾▾
This calculator feature is sunsetted on the wiki. It may not see further updates, but will be present on articles for the time being since some people still find use for them. See User blog:Cephalon Scientia/Sunsetting of Maximization Calculators for more details.
Inflict a target with a pox of Corrosive spores. Spread spores to nearby enemies by destroying them or killing their host. The longer the Spore spreads, its damage will increase.
Saryn expends 25energy to infects an enemy target within 30 / 40 / 50 / 60 meters with 2 / 2 / 3 / 3 virulent spores for an infinite duration. Each individual spore inflicts Corrosive damage per second with a 50%CorrosiveStatus Chance, lasting until the spores themselves or the infected enemy is destroyed.
Saryn's disease spreads its infection rapidly, grows evermore lethal, and decays in the absence of hosts over the course of the epidemic:
Shooting or hitting a spore directly bursts its membrane to release infectious pus, which regrows the spore on its host and transmits 1 spore to all nearby enemies within 10 / 12 / 14 / 16 meters; infected enemies can carry up to 3 spores via transmission from another enemy.
Spores can spread by directly bursting them with weapons, abilities, and Bullet Jump. Enemy attacks can also burst spores on contact.
Spread bypasses obstacles in the environment and damage does not diminish with distance.
All spores on an infected enemy will burst and spread if any of the following conditions are met:
Spores' initial target is killed by any source.
Players landing the killing blow on any infected enemies.
Infected enemies are killed by Molt's explosion damage.
Saryn's weapons hitting anywhere on the infected enemies' body while Toxic Lash is active.
Infected enemies are killed by any source while sickened by Miasma.
Spores do not spread if enemies infected via transmission are killed by Spores' damage over time.
When the outbreak first begins, damage per second starts at 6 / 8 / 8 / 10Corrosive damage; for every second Spores remain active, damage per second increases by 1 / 1.25 / 1.5 / 2Corrosive damage per infected enemy, up to a damage growth cap of 7 infected enemies. Current damage per second is uniform across all active spores and will apply to newly infected enemies.
Current damage per second is hard-capped at 100,000 damage.
While Spores is active, a stylized infection meter appears above Saryn's ability icons on the HUD, indicating the current damage per second and tracks the number of infected enemies in the mission affected by spores belonging to the player.
When zero infected enemies remain, Spores' current damage per second is instantly reduced by 20% then decays at 10% of the new total every half second until it reaches the initial damage amount. Damage decay stops when at least one enemy is infected by Spores.
Nullifying effects (such as entering Sanctuary Onslaught Data-Conduits) increases the decay rate to 30% per half second.
Reset decay is inversely affected by Ability Strength, meaning more Strength reduces the amount consumed.
Damage decay rate is inversely affected by Ability Duration, meaning more Duration reduces the amount of damage decay per half second.
Current damage per second is visibly subtracted from the meter whilst a red flashing "decaying" warning message replaces the counter for number of infected enemies.
The infection meter disappears when it reaches the initial damage amount.
If Spores is still active, recasting Spores on any enemy consumes 20% of current damage per second from the infection meter and casts Spores for 50% reduced energy cost. Recasting on an infected enemy grows a new set of spores on the target, which carries up to 12 spores via recasting Spores on it.
Recast decay is inversely affected by Ability Strength, meaning more Strength reduces the amount consumed.
All spores destroyed via melee weapon contribute to the melee combo counter.
Each instance of Spores has its own Ability Strength value from when it was casted, and be independent from other instances.
For example, if an instance of Spores is casted when Energy Conversion is activated, that instance will retain Status chance and Damage Growth with Ability Strength bonus.
If another instance of Spores is casted, when there is no bonus, the second instance will have lower Status chance and Damage Growth, even while the first instance from above is still active.
All spores share the same accumulated damage per second, though each instance could contribute Damage Growth at different rate.
When Spores spread to other enemies, the subsequent instances will retain Status chance and Damage Growth from their original instance. Strong instance spreads strong instances, and vice versa.
Spores being carried by enemies will not be replaced by another spore via transmission.
If an enemy is carrying spores from multiple instances with different Strength values, damage per second will be contributed by the instance with the highest Damage Growth.
Ability Synergy:
Toxic Lash can make spores burst with every attack, even without direct hits.
Hitting a spore while Toxic Lash is active applies an additional Toxin proc.
Miasma deals 400% damage to enemies affected by Spores.
Spores is a one-handed action. As such, it can be used while performing various maneuvers and actions without interruption.
If the initial target dies before the spores appear, energy used for Spores will be refunded.
Venom Dose is a Warframe Augment Mod for Saryn that allows Spores to be held on cast, creating a wave of energy traveling outward from the user that temporarily grants the caster and nearby allies additional Corrosive damage to all attacks.
Cast on an enemy in the middle of a crowd and promptly kill it or use one of the many methods to spread the spores.
Each spore inflicts damage per second and Corrosive status effect on proc, which is tripled on an enemy carrying three spores from a max rank Spores cast or accumulated from transmission from other infected enemies.
Infect at least 7 enemies to maximize damage growth, allowing Spores to reach higher damage per second counts over time.
Mod for Ability Strength to increase initial damage, damage growth per enemy, status chance, while reducing the reset decay on recast or on zero infected present.
Status chance can reach 100% with 200% Ability Strength.
Recast Spores several times to inflict an enemy with up to 12 spores to strip its Armor quickly, deal more damage per second instances, and provide more spores to spread.
However, note that each recast will consume a percentage of damage per second stored in your infection meter.
Using melee to hit enemies makes it easier to burst spores, compared to firearms, especially with Range mods, e.g. Reach (Primed).
Use Toxic Lash to spread spores on an infected enemy on every hit using your gun or melee.
Cast Miasma to inflict quadruple damage to all enemies infected by Spores within range.
Can be used to destroy Corpus cameras and (active) turrets. A spore will appear but a camera dies on the first tick.
When combined with AoE weapons (such as Ignis and Embolist, which both deal DoT, increased by Saryn's passive), the spores will pop very easily, quickly spreading Corrosive procs.
Thrown secondaries loaded with Concealed Explosives are also effective and economical at quickly popping Spores, especially when combined with Fulmination (Primed).
The ability synergizes well with Nova's Molecular Prime, both spreading and weakening enemies until one dies and causes a series of chain explosions and effectively quartering enemy survivability.
Spores is excellent for bosses with shields to prevent them from recovering.
This is quite effective against Ambulas since it targets the torso and, like all MOAs, he takes three times damage on that body part.
Equipping a sentinel with the Sweeper weapon increases this chance.
Spores that are popped on a target's weak point, like the head, will do extra damage based on the respective damage multiplier.
For example, if you pop a Spore on an enemy's head, it will deal 50 damage (25 x 2 damage multiplier).
Spores' DoT ticks are unaffected by weak spots.
AoE damage from popping spores is unaffected by weak spots. Nearby enemies will still only take 25 Corrosive damage from popped spores on weak spots.
A Range-based Spores build is good for earning Focus points in stage-less endless missions such as Survival, Disruption and Void Flood, as long as Saryn can keep it from decaying.
Active spores can help fill the self-revive gauge from the Unairu school's Last Gasp.
Saryn expends 50energy to shed her skin, removing all existing status effects and increasing her Movement Speed by 30% / 35% / 40% / 50% for 3.5 / 4 / 4.5 / 5 seconds, while leaving behind a decoy with 400shields and 150 / 300 / 400 / 500health that draws enemy fire for 14 / 24 / 32 / 40 seconds. When deployed, the decoy is Invulnerable for 1.5 / 2 / 3 / 3 seconds, during which all incoming damage absorbed by it is converted and added to its health. The decoy will explode if it loses all of its hitpoints, if its duration expires or if the ability is cast again, inflicting 240 / 300 / 350 / 400Toxin damage with 100%Toxinstatus chance to all enemies within 5 / 6 / 7 / 10 meters from it. A maximum of 1 Molt can exist.
Explosion damage does not bypass obstacles in the environment and diminishes with distance.
Recasting will activate will detonate the Molt and spawn a new one.
Does not have a cast time or animation.
Molt's decoy is placed at Saryn's current position, mirroring her pose and elevation.
Elemental augment mods, such as Ember's Fireball Frenzy, can be applied to Molt. The damage augment will not affect the explosion damage or damage type upon Molt's expiration.
Molt cannot be knocked down or moved, and acts as a physical object, unlike Loki's Decoy.
Molt will slowly vaporize and dissipate for its duration, eventually exploding once it nearly vanishes.
Casting Molt can be done while performing any action without interrupting it, including reloading, charging, shooting, maneuvering, and while on a zipline.
Can be cast in all states (except while upside down in a flip jump or while dodging) and can be reused instantly.
Subsuming Saryn to the Helminth will offer Molt and its augments to be used by other Warframes.
Using during a well timed jump can result it being low enough for enemies to target, such as Infested or Melee units, but be more protected from most melee attacks. (Ancients will still be able to reach, as well as the knockback damage from Leapers).
Place Molt in locations which can protect it from enemy attacks to maximize its survival.
Limbo can utilize this ability by casting Banish on the decoy, granting it immunity to all attacks that do not affect targets in the Rift Plane.
If Molt is closer to the enemy than the player, enemies will (normally) focus it. Applies to the caster as well as other players, unless they're using aggro-increasing abilities such as Nyx's Absorb or Rhino's Iron Skin.
It can be used as protection from enemy fire, when you revive an downed teammate.
Bugs
When knocked back by an Ancient, the physical target of the decoy will move, but the model remains in place. This can be seen while having Enemy Sense and Enemy Radar equipped while seeing the decoy (as a friendly blip) against a group of infested.
For clients, Molt will sometimes be in a default standing position when deployed.
Saryn expends 50energy to imbue all her weapons with potent toxins for 20 / 25 / 35 / 45 seconds, dealing an extra hit for 20% / 24% / 26% / 30% of the weapon's total damage as Toxin damage (doubled for melee weapons), which has a guaranteed Toxin proc on every strike.
Toxic Lash adds an extra Toxin attack that scales with weapon damage on hit, before health and armor resistances.
For example, an unmodded weapon that hits for 200 damage with a Rank 3 Toxic Lash and a Rank 5 Intensify, Toxic Lash will deal: 200 × 0.3 × 1.3 = 78Toxin damage which ticks for 78 × 0.5 = 39Toxin damage per second.
Toxin mods will apply their toxin mod multiplier to Toxic Lash's Toxin ticks, regardless if they are combined into other elements.
Extra Toxin damage does not combine with weapon elements.
Faction Damage Mods, after first applying, will multiply Toxic Lash's hit a second time, and multiply its Toxin ticks a third time, effectively triple-dipping.
Status Duration Mods and Saryn's own passive affect the duration of the Toxin proc.
Damage is affected by Ancient Disruptor auras and other enemies that reduce ability damage, unlike other weapon buffing skills.
Toxic Lash's damage instance does not charge Incarnon Transmutation.
Cast animation of ~1 second is affected by Casting Speed.
Saryn is immune to crowd control during the cast animation.
Casting Toxic Lash is a one-handed action that can be done while performing many actions without interrupting them, including reloading, charging, shooting, maneuvering, and while on a zipline.
Can be recast to refresh its duration.
Ability Synergy:
Toxic Lash can make Spores burst with every attack, even without direct hits.
Hitting a spore while Toxic Lash is active applies an additional Toxin proc.
Contagion Cloud is a Warframe Augment Mod for Saryn that causes kills made with Toxic Lash, and damage over time effects generated by it, to leave behind a poisonous cloud that deals Toxin damage over time to enemies within it. Melee kills double the damage dealt by the cloud.
Toxic Lash is an invaluable ability for players who were not able to collect a Melee Toxin mod or not capable of equipping such on Melee weapons, in which the ability becomes a suitable replacement for those in need of direct health damage.
Toxic Lash's damage takes elemental mods and buffs like Venom Dose into account, even on damage instances normally unaffected by elemental mods, such as the radial damage of slam attacks, explode on death mods such as Acid Shells, and mods like Concealed Explosives. This makes it possible for them to deal vastly more damage than normal through Toxic Lash, which is especially useful for Arca Titron, Tenet Exec, and Sobek. (Possibly a bug.)
Maximization
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Bugs
While playing on client (Not as host), the use of toxic lash significantly reduces critical hit chance, to the point where having over 400% critical chance will only cause occasional critical hits, not guaranteed red crits as it should. This will only persist as long as toxic lash is active.
Saryn expends 75energy to pollutes the environment with a viral mist, briefly Stunning enemies within 10 / 12 / 16 / 20 meters and sickening them for 6 seconds, dealing 110 / 125 / 135 / 150Viral damage per second, with 100%Viralstatus chance on cast.
Cast animation of ~1.5 seconds is affected by Casting Speed.
Saryn is immune to crowd control during the cast animation.
Miasma cannot stun enemies again if they are still being affected by a previous cast, but will refresh the sickness' duration.
Ability Synergy: Miasma deals 400% damage to enemies affected by Spores, and Spored enemies that die while sickened by Miasma will spread Spores.
Casting Miasma can be done while sliding and in mid-air, but will interrupt any other action and will force Saryn in place for the entire animation.
Use Spores first to start shredding armor (if any), then attack with Toxic Lash to inflict Toxin procs on enemies, and follow up with Miasma to deal quadruple damage and a guaranteed ViralStatus Effect proc to increase damage dealt to enemies' health, so Toxin damage can eat their health up quicker.
When using Miasma, be careful to not get knocked down during the cast animation, as once up again, Saryn will automatically repeat the cast animation, during this repeat animation she will take damage as normal, leaving you extremely vulnerable.
Miasma will not interrupt aim glide. Left/right directional input will be stopped, but the aim glide itself will continue straight as normal.
Bugs
Casting Miasma immediately after casting either Spores or Toxic Lash will cause Miasma's casting animation to bug, causing the player to be able to move while casting and rapidly cast Miasma.
Being knocked down during the casting animation causes Saryn to repeat the animation upon standing up.
Systems Blueprint
Chassis Blueprint
Neuroptics Blueprint
50
Market Price: 
Blueprints Price: 
Gyre in terms of height.
Saryn's weapons and abilities last 25% longer.
25
Strength:6 / 8 / 8 / 10 (initial damage)
Corrosive status chance)
Duration:10% (damage decay rate)
Range:30 / 40 / 50 / 60 m (cast range)
Toxin explosion damage)
Viral damage)
Ash (
Prime) • 
Atlas (
Prime) • 
Banshee (
Prime) • 
Baruuk (
Prime) • 
Caliban • 
Chroma (
Prime) • 
Citrine • 
Dagath • 
Dante • 
Ember (
Prime) • 
Equinox (
Prime) • 
Excalibur (
Umbra, 
Prime) • 
Frost (
Prime) • 
Gara (
Prime) • 
Garuda (
Prime) • 
Gauss (
Prime) • 
Grendel (
Prime) • 
Gyre • 
Harrow (
Prime) • 
Hildryn (
Prime) • 
Hydroid (
Prime) • 
Inaros (
Prime) • 
Ivara (
Prime) • 
Khora (
Prime) • 
Kullervo • 
Lavos • 
Limbo (
Prime) • 
Loki (
Prime) • 
Mag (
Prime) • 
Mesa (
Prime) • 
Mirage (
Prime) • 
Nekros (
Prime) • 
Nezha (
Prime) • 
Nidus (
Prime) • 
Nova (
Prime) • 
Nyx (
Prime) • 
Oberon (
Prime) • 
Octavia (
Prime) • 
Protea • 
Qorvex • 
Revenant (
Prime) • 
Rhino (
Prime) • 
Prime) • 
Sevagoth • 
Styanax • 
Titania (
Prime) • 
Trinity (
Prime) • 
Valkyr (
Prime) • 
Vauban (
Prime) • 
Volt (
Prime) • 
Voruna • 
Wisp (
Prime) • 
Wukong (
Prime) • 
Xaku • 
Yareli • 
Zephyr (
Prime)