Each strike of this infested glaive infects its target with viral pathogens. Occasionally, it discharges the spores of rabid, enemy-seeking maggots, either in-flight or on contact with an enemy.

The Pathocyst is an Infestation b.svgInfested Glaive that is the signature weapon of the Zealoid Prelate, boasting innate DmgViralSmall64.pngViral damage and high status chance, and releases Maggots when attacking enemies or when thrown.

Characteristics[edit | edit source]

This weapon deals primarily DmgViralSmall64.pngViral damage.


  • Highest base damage of all glaives.
  • Good critical chance.
  • Above average critical multiplier.
  • Tied with PrimeGlaive.pngGlaive Prime and PunctureGlaive.pngCerata for the second-highest status chance of all glaives, behind CrpGlaive.pngFalcor.
  • Can be wielded in-tandem with a single-handed secondary weapon.
  • Holding the melee button throws the glaive, which can bounce up to three times or travels up to 30 meters before returning to the user, damaging anyone in its path. Meleeing while the glaive is in mid-flight commands it to return.
    • Primary and secondary weapons can be fired and reloaded normally with a thrown glaive, and retrieving the glaive does not interrupt these actions. Additional throws can also be "buffered" while the glaive is in mid-flight.
    • Thrown glaive is silent.
    • Heavy Attacks, or melee attacks while wielded in-tandem with a secondary weapon, while the glaive is in mid-flight produces a 4.9 meter explosion and forces the glaive to return.
      • Explosion inflicts a guaranteed DmgViralSmall64.pngViral proc.
      • No damage falloff.
    • During flight or when striking an enemy, the glaive drops Infested pods which quickly hatch into Maggots that last for 7 seconds and will fight alongside the player.
      • Maggots can latch onto enemies and stagger them.
      • Maggots may also appear on any normal attack done to enemies.
  • Can be wielded in-tandem with a single-handed secondary weapon.
  • Can use the Glaive-exclusive mods Mod TT 20px.pngCombo Fury, Mod TT 20px.pngPower Throw, Mod TT 20px.pngQuick Return (Mod TT 20px.pngVolatile), Mod TT 20px.pngRebound (Mod TT 20px.pngVolatile), and Mod TT 20px.pngWhirlwind.
  • Innate V and D polarities.


  • Innate DmgViralSmall64.pngViral damage – less effective against Infested and Machinery.
  • Low DmgPunctureSmall64.pngPuncture damage – less effective against armor.
  • Slowest attack speed of all glaives.
  • Cannot use melee attacks or block while the glaive is in mid-flight.
  • Explosion inflicts self-stagger.
  • Thrown glaive has no punch through.
  • Spawned maggots:
    • Deal negligible damage.
    • Alerts enemies, despite the weapon being silent.
    • Have a limited lifespan.


Pathocyst's main blueprint and components can be obtained from defeating Zealoid Prelate on Exequias, Deimos. All parts are tradeable between players.

Drop Chance Expected Nearly Guaranteed
Main Blueprint 33.33% 7 – 8 kills 25 ± 6 kills
Subcortex 33.33%
Blade 33.33%

All drop rates data is obtained from DE's official droptables.

Expected refers to total number of kills a player can expect to need in order to receive at least one Main Blueprint and Subcortex, and at least two Blades.
Nearly Guaranteed refers to the total number of kills a player needs to obtain a 99%, 99.9%, and 99.99% probability to receive at least one Main Blueprint and Subcortex, and at least two Blades.

For more detailed definitions and information on how these number were obtained, visit here.

Manufacturing Requirements
Time: 24 hrs
Rush: Platinum64.png 25
MarketIcon.png Market Price: Platinum64.png N/A Blueprint2.svg Blueprints Price:N/A

Notes[edit | edit source]

  • Acquired blueprints can be sold for Credits64.png2,500 each while its components can be sold for Credits64.png3,500 each.
  • Maggots spawned by the Pathocyst do not interact with NidusIcon272.pngNidus's abilities or the Strain Mod Set.
  • Spawned maggots do not benefit from elemental boost augments such as Mod TT 20px.pngSmite Infusion, they can benefit from some ally-related buffs such as Wisp's Reservoirs.
  • Leveling the Pathocyst through stealth can be very challenging, due to maggots spawning sometimes through stealth finishers, and many more spawning through thrown attacks, which will alert enemies. Exploding maggots, while dealing low damage, may immediately thrust enemies out of a 'sleep state' (eg Sleep Arrow from Quiver130xDark.pngQuiver or RestRage130xDark.pngRest & Rage) with no wakeup animation, who may then see dead bodies.
    • It is important to mod the weapon with fire rate and finisher damage to ensure one-shot kills on enemies, but also extra awareness of which enemies in range are asleep or out of visual range, and which are not. Maggots may also suddenly sprint very quickly, darting around a corner if they detect enemies and then getting shot at, alerting the area.
  • Properties of exploding Maggots:
  • The Pathocyst is the only Glaive that simply gains bonus damage on thrown attacks. All other Glaive weapons also gain bonus Status and/or boosts to Crits.

Tips[edit | edit source]

  • The main benefit of the spawned maggots is crowd control; Enemies will be briefly distracted by running maggots or stunned when they manage to latch onto them, but due to their limited life spawn they won't last long.
  • Modding the Pathocyst with high-status chance and DmgColdSmall64.pngCold damage will extend the duration of the stun when maggots latch, assuming the cold damage procs. This can slightly boost the effectiveness of latched maggots.

Gallery[edit | edit source]

Media[edit | edit source]

Patch History[edit | edit source]

Hotfix 29.6.5

  • Fixed Pathocyst Infested pod sound looping when pods are created but do not spawn a maggot.

Update 29.5

  • Added guaranteed Viral proc to Heavy Attack Detonation.
  • Reduced Max self CC from Knocked Down to Stagger.
  • Removed falloff from Throw Explosion and Charged Throw Explosion damage.
  • (Undocumented) Throw Explosion Damage and Charged Throw Explosion damage increased from 786 to 1,572 Viral damage.

Hotfix 29.3.2

  • Fixed a heavy spot-load occurring when equipping the Pathocyst in the Arsenal.

Hotfix 27.2.2
Reduced the following AoE weapons Radial Damage Falloff from central impact that were all previously 90%:

  • Pathocyst: 50%

Update 27.2

Self Damage Changes

We are getting rid of Self Damage and replacing it with something else: instead of Self Damage, it’s now ‘Stagger’. This change completely removes the chance of killing yourself, and instead now creates scenarios where you will interrupt yourself - or ‘Stagger’ - to varying degrees if you aren’t careful.

The degrees of Self-Interrupt start with a small stumble all the way to full knockdown depending on how close you are to the center of explosion. Any Mods referring to Self Damage will be converted to acknowledge Stagger.

With this Self-Interrupt system, we have added dozens of new recovery animations that harness a ninja-like recovery experience. By pressing ‘Jump’ at the correct time, you can execute a ninja-skill-based knockdown recovery to ALL in-game knockdowns. This ninja recovery window is indicated by a glowing FX on your Warframe.

In the original Dev Workshop, we said:
As a result of this overall systemic change, Weapons with Stagger will be getting approximately a 20% buff in Damage, with any weapons with AOE receiving a 50% Radial Damage Falloff from central impact.

This is no longer accurate after continued testing. What we are doing now is:

No damage buffs have been added, but any weapons with AOE are receiving ~20% increase in Radius. Additionally, AOE weapons are receiving a 90% Radial Damage Falloff from central impact. This means on the very outer section of the explosion Radius 10% of the Damage will be dealt. Tactics will be deadly - aim true, Tenno.

Why: Several players brought up the history of the Tonkor and we want to make sure we ship this change in a place that’s conservative in its starting point from a balance perspective. The complete removal of Self Damage does change the pace of destruction with some of the game’s most powerful weapons, so we want to make sure we can iterate upwardly instead of releasing a bonanza of explosions with no other choices.

Update 26.0
As a general note, self damage has been removed from Glaive power throws. As this decision made it through the testing pipeline, some mentioned this impacts a specific Chroma interaction, but positively impacts 41 other Warframes.

  • Damage increased from 82 to 262.
  • Slam Attack increased from 82 to 786.
  • Slide Attack increased from 410 to 524.
  • Parry Angle set to 55.
  • Follow Through increased from 0.5 to 0.7.

Update 25.8

  • Added new “fast whooshing” sounds to the Pathocyst.

Hotfix 25.7.7

  • (Undocumented) Introduced.

Last updated: Update 26.0

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