An instrument of unrelenting harm.

The Lesion is an Infested polearm based on the Tipedo Tipedo. Upon inflicting a Status Effect on its target, the Lesion gains bonuses to its Attack Speed and bonus Toxin b Toxin damage, which coupled with its primary focus on Slash b Slash damage makes it a dangerous weapon against lightly-armored targets.

This weapon can be sold for Credits646,000.

Manufacturing Requirements
Time: 12 hrs
Rush: Platinum64 35
MarketIcon Market Price: Platinum64 150 Blueprint2 Blueprints Price:Credits6425,000


This weapon deals primarily Slash b Slash damage.


  • Second highest damage of all polearms, behind GrnHalberd Kesheg.
  • Highest status chance of all polearms.
  • Medium range attacks with a wide radius.
  • Has an innate attack speed increase and bonus Toxin b Toxin damage upon landing a successful attack with a status proc.
    • Additional Toxin b Toxin damage added will combine with any primary elements (or secondary elements with Toxin b Toxin) on the weapon.
  • Stance slot has Zenurik Pol polarity, matches Mod TT 20pxShimmering Blight stance.
  • Has a Madurai Pol polarity.



  • On dealing status procs on an enemy, the Lesion has a unique feature whereby it gains 15% additional attack speed for 6 seconds, as well as 100% Toxin b Toxin damage.
    • Attack speed buff is additive to attack speed mods on the weapon.
    • This buff does not stack with repeated status procs.
    • This buff duration is not refreshed upon inflicting procs while the buff is still active. The buff must first expire before another instance can be activated.
    • The Toxin b Toxin damage is additive to other elemental mods on the weapon.



  • Lesion is any abnormal damage or change in an organism's tissue, usually the result of injury or disease. It is derived from the Latin word laesio, which simply means "injury".
  • Though looking quite similar in design and length to the Tipedo Tipedo,the Lesion's crafting component, the Lesion is labelled as a polearm while the Tipedo is a staff.
  • The Lesion has a non-static model; the "jaws" of the weapon close when not actively equipped, will open upon being wielded, and without a Stance equipped, the jaws will visibly "bite" on the thrusting second and fourth strikes of the combo.


  • The Lesion, shown in the Update 18.5 Teaser
  • Inaros wielding a Lesion in the Update 18.5 Teaser
  • 18.5 Hub's Weapon Teaser

Lesion Skins

Patch History

Update 22.6
  • Fixed polearms clipping on some Warframes when using the standard holster position.

Update 18.5

  • Introduced.

Last updated: Hotfix 23.2.1

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