An instrument of unrelenting harm. If Lesion tastes blood, it becomes invigorated with faster Attack Speed and increased DmgToxinSmall64 Toxin Damage.

The Lesion is an Infested polearm based on the Tipedo Tipedo. Upon inflicting a Status Effect on its target, the Lesion gains bonuses to its Attack Speed and bonus DmgToxinSmall64 Toxin damage, which coupled with its primary focus on DmgSlashSmall64 Slash damage makes it a dangerous weapon against lightly-armored targets.


  • This weapon deals primarily DmgSlashSmall64 Slash damage.
  • Passive: Gains 15% attack speed and 100% DmgToxinSmall64 Toxin damage bonuses for 6 seconds upon landing a successful attack with a status proc.
    • Additional DmgToxinSmall64 Toxin damage added will combine with any primary elements (or secondary elements with DmgToxinSmall64 Toxin) on the weapon.
  • Stance slot has Zenurik Pol polarity, matching Mod TT 20px Shimmering Blight and Mod TT 20px Argent Scourge (Conclave only) stance.
  • Has a Madurai Pol polarity.

Advantages over other Melee weapons (excluding modular weapons):

  • Normal Attack (wiki attack index 1)
    • Above average total damage (237)
    • Above average attack range (2.70 m)
    • Very high status chance (37.00%)

Disadvantages over other Melee weapons (excluding modular weapons):

  • Normal Attack (wiki attack index 1)
    • Low crit chance (15.00%)
    • Low disposition (●●○○○ (0.80x))

See WARFRAME Wiki:Stat Comparison/Percentiles for more details.


The Lesion's blueprint can be purchased from the Market.

Manufacturing Requirements
📝 Edit blueprint requirements
Tipedo Tipedo
Plastids Plastids
Neurodes Neurodes
NanoSpores Nano Spores
Time: 12 Hour(s)
Rush: PlatinumLarge 35
MarketIcon Market Price: PlatinumLarge 150 Blueprint2 Blueprints Price:Credits25,000

This weapon can be sold for Credits64 6,000.


  • On dealing status procs on an enemy, the Lesion has a unique feature whereby it gains 15% additional attack speed for 6 seconds, as well as 100% DmgToxinSmall64 Toxin damage.
    • Attack speed buff is additive to attack speed mods on the weapon.
    • This buff does not stack with repeated status procs.
    • This buff duration is not refreshed upon inflicting procs while the buff is still active. The buff must first expire before another instance can be activated.
    • The DmgToxinSmall64 Toxin damage is additive to other elemental mods on the weapon.
    • Due to a bug, this passive is unlikely to work if you are not the host of the mission.


  • The weapon's DmgToxinSmall64 Toxin buff synergizes well with DmgCorrosiveSmall64 Corrosive, DmgGasSmall64 Gas, or DmgViralSmall64 Viral builds.
  • Synergizes well with SarynIcon272 Saryn: her passive increases the duration of status procs by 25% (adding to their total damage) and ToxicLash130xWhite Toxic Lash guarantees procs along with adding even more DmgToxinSmall64 Toxin damage.
  • The attack speed buff along with the weapon's high status chance allows the Lesion to proc multiple statuses quickly, good for limited crowd control and/or Mod TT 20px Condition Overload.


  • A Lesion is any abnormal damage or change in an organism's tissue, usually the result of injury or disease. It is derived from the Latin word laesio, which simply means "injury".
  • Though looking quite similar in design and length to the Tipedo Tipedo,the Lesion's crafting component, the Lesion is labelled as a polearm while the Tipedo is a staff.
  • The Lesion has a non-static model; the "jaws" of the weapon close when not actively equipped, will open upon being wielded, and without a Stance equipped, the jaws will visibly "bite" on the thrusting second and fourth strikes of the combo.


Lesion Skins


Patch History[]

Update 26.0 (2019-10-31)

  • Mastery Rank increased from 7 to 9.
  • Damage increased from 100 to 237.
  • Range increased from 1.5 to 2.7.
  • Status Chance increased from 30% to 37%.
  • Critical Chance increased from 5% to 15%.
  • Slam Attack increased from 200 to 711.
  • Slide Attack increased from 222 to 474.
  • Parry Angle set to 55.
  • Follow Through reduced from 0.8 to 0.6.

Update 22.6 (2017-12-07)

  • Fixed polearms clipping on some Warframes when using the standard holster position.

Update 18.5 (2016-03-04)

  • Introduced.

Last updated: Update 26.0 (2019-10-31)