An instrument of unrelenting harm.

The Lesion is an Infested polearm based on the Tipedo Tipedo. Upon inflicting a Status Effect on its target, the Lesion gains bonuses to its Attack Speed and bonus Toxin b Toxin damage, which coupled with its primary focus on Slash b Slash damage makes it a dangerous weapon against lightly-armored targets.

This weapon can be sold for Credits646,000.

Manufacturing Requirements
Time: 12 hrs
Rush: Platinum64 35
MarketIcon Market Price: Platinum64 150 Blueprint2 Blueprints Price:Credits6425,000


This weapon deals primarily Slash b Slash damage.




  • On dealing status procs on an enemy, the Lesion has a unique feature whereby it gains 15% additional attack speed for 6 seconds, as well as 100% Toxin b Toxin damage.
    • Attack speed buff is additive to attack speed mods on the weapon.
    • This buff does not stack with repeated status procs.
    • This buff duration is not refreshed upon inflicting procs while the buff is still active. The buff must first expire before another instance can be activated.
    • The Toxin b Toxin damage is additive to other elemental mods on the weapon.
    • Due to a bug, this passive is unlikely to work if you are not the host of the mission.


  • The weapon's Toxin b Toxin buff synergizes well with Corrosive b Corrosive, Gas b Gas, or Viral b Viral builds.
  • Synergizes well with SarynIcon272 Saryn: her passive increases the duration of status procs by 25% (adding to their total damage) and ToxicLash130xDark Toxic Lash guarantees procs along with adding even more Toxin b Toxin damage.
  • The Attack Speed buff along with the weapon's high status chance allows the Lesion to proc multiple statuses quickly, good for limited crowd control and/or Mod TT 20pxCondition Overload.


  • Lesion is any abnormal damage or change in an organism's tissue, usually the result of injury or disease. It is derived from the Latin word laesio, which simply means "injury".
  • Though looking quite similar in design and length to the Tipedo Tipedo,the Lesion's crafting component, the Lesion is labelled as a polearm while the Tipedo is a staff.
  • The Lesion has a non-static model; the "jaws" of the weapon close when not actively equipped, will open upon being wielded, and without a Stance equipped, the jaws will visibly "bite" on the thrusting second and fourth strikes of the combo.


  • The Lesion, shown in the Update 18.5 Teaser
  • Inaros wielding a Lesion in the Update 18.5 Teaser
  • 18.5 Hub's Weapon Teaser

Lesion Skins

Patch HistoryEdit

Update 26.0

  • Mastery Rank increased from 7 to 9.
  • Damage increased from 100 to 237.
  • Range increased from 1.5 to 2.7.
  • Status Chance increased from 30% to 37%.
  • Critical Chance increased from 5% to 15%.
  • Slam Attack increased from 200 to 711.
  • Slide Attack increased from 222 to 474.
  • Parry Angle set to 55.
  • Follow Through reduced from 0.8 to 0.6.

Update 22.6

  • Fixed polearms clipping on some Warframes when using the standard holster position.

Update 18.5

  • Introduced.

Last updated: Update 26.0

Community content is available under CC-BY-SA unless otherwise noted.