Bosses

Main article: Captain Vor

Captain Vor is the Grineer officer responsible for the players' awakening in the opening moments of WARFRAME. He is also the first boss that players will be required to defeat.

Vor is one of the few figures in the Origin System that understand ancient Orokin technology, and is capable of utilizing it and merging it with Grineer technology to create offensive weapons such as his trademark Seer pistol and his armor, which is powered by a Void Key. This "Janus Key" also grants him a powerful ranged beam attack, impenetrable shielding and the ability to teleport.

Captain Vor can be encountered in three locations currently, making him the most recurring boss in the game aside from the assassins. First appearing at the end of the Vor's Prize quest and thus being the first boss that players must fight, he also serves as the boss of Mercury; he then appears again, somehow fully alive, on Ceres alongside Lieutenant Lech Kril, then appearing later yet again as a Corrupted version of himself within the Void.

• On Tolstoj, Mercury, a successful assassination will reward the Seer blueprint and components upon his defeat, and may also drop Orokin Cells. There is also a small chance of being rewarded a Cronus blueprint.
• On Exta, Ceres, the player will receive Frost component blueprints.

Main article: Councilor Vay Hek

Councilor Vay Hek is the administrator of Earth on behalf of the Grineer Queens. He has been marked by the Lotus for assassination for upsetting the balance in the system by killing several political opponents. He is also known for being heavily modified with Grineer alterations, having little noticeable remaining flesh while he rides in his giant Terra Frame.

He can be found on the Oro node, which can be accessed only by players of Mastery Rank 5 or higher. Upon defeating him and completing the mission, players will receive Hydroid component blueprints. Upon death, Councilor Vay Hek has a chance of dropping Neurodes and Orokin Cells.

Main article: Lieutenant Lech Kril

Lieutenant Lech Kril is the boss of Mars, and a dual boss on Ceres alongside Captain Vor. A revered war hero clad in impenetrable armor and armed with his signature hammer and Cold/ Heat abilities, Lech Kril is a formidable adversary for anyone who opposes him.

• On Mars, a successful assassination will reward Excalibur's components.
• On Ceres, a successful assassination will reward Frost's components.

Main article: General Sargas Ruk

General Sargas Ruk is the final boss of the Saturn system. The head of one of the Grineer Artifact extraction projects, Sargas Ruk was targeted by the Lotus for annexing Tenno-controlled dig sites. Ruk enjoys Grineer augmentation, even going as far as replacing the lower part of his right arm with a massive flamethrower and his normal vision with a single augmentation in the center of his helmet. He can be found in the mission Tethys. His suit is invulnerable, except for the cooling vents that open after he uses his abilities. These weak points will change after a set amount of damage is received. After defeating him and finishing the mission the player will receive an Ember component blueprint. He has an increased chance to drop an Orokin Cell upon death.

Main article: Tyl Regor

Tyl Regor is the final boss of the Uranus system and the head researcher focusing on Grineer gene repair in an attempt to reverse the negative effects from excessive cloning. He was targeted by the Lotus in order to slow down this progress, ensuring that the Grineer do not become more powerful. He can be found on the mission Titania. After defeating him and finishing the mission, the player will receive Equinox component blueprints.

Main article: Kela De Thaym

Kela De Thaym is the final boss of the Sedna planet. Bloodthirsty and sadistic, De Thaym owns the combat arena known as Rathuum, where would-be defectors are forced to fight for their freedom against Kela's Executioners, to the delight of her audience. She can be found on the mission Merrow. Standing well above her subordinates, Kela is as agile as she is fierce, leaping from platform to platform while launching salvoes of rockets and grenades. After defeating her and finishing the mission, the player will receive Saryn component blueprints. Kela will also drop an Executioner-themed mod and has a chance to drop an Orokin Cell upon death.

Main article: Balor Fomorian

The Balor Fomorian is the strongest class of all known Fomorian types, according to Councilor Vay Hek. They are considered the most powerful vessels in the Origin System. Bristling with immense firepower and formidable armor, they are capable of destroying a capital ship in a matter of seconds. Their power has made them the repeated targets of the Tenno, to prevent Grineer influence from spreading.

They are occasionally available in a Fomorian Sabotage alert as a Grineer Archwing boss, where the player may be rewarded with Imperator Vandal components, Endo, or Archwing mods upon defeating the Fomorian and extracting.

Main article: Jackal

Jackal is the final boss of the Venus system, and represents the first Corpus boss that players encounter. Although a more bulky and old model compared to more recent Corpus robotics, the Jackal possesses invulnerable shields, a giant shockwave ability to knock players down, and one of the most powerful corpus weapons, the Plasma Grenade Cluster. Dissected models of the Jackal can be found in some Grineer tilesets, either showing that the Grineer have interest in utilizing Corpus technology, or that they have simply purchased merchandise.It can be found on the mission Fossa. After defeating it and finishing the mission, the player will receive  Rhino component blueprints.

Main article: The Sergeant

The Sergeant, formerly known as Sgt. Nef Anyo before Update 16.4, is the final boss of Phobos system, formerly Mars. He is in charge of the Corpus solar rail systems, using them to obtain Cryopods with dormant Warframes for resale to rogue scientists and splinter groups. When confronted by the player during the mission, he has a very aggressive tone towards the Tenno and warns the player that they are making a fatal mistake by attempting his assassination. He also may demand information regarding Orokin secrets, or make fun of the player's Warframe or teammates.

Main article: Alad V

Alad V was a member of the Corpus Board of Directors and the head of Grineer Relations. He is the most recurring Corpus boss in terms of his involvements with various Events. Originally the creator of the ambitious Zanuka Project, an initiative to create advanced robotics by using Warframe components, its eventual failure saw him removed from the Board of Directors and replaced with his longtime rival, Frohd Bek.

Disgraced and on the run from his former Corpus backers, Alad eventually became obsessed with the promise of biological ascendancy via The Infestation, with the hopes of dominating the Origin System through his so-called "Mutalist Empire". His mind falling prey to the Infestation, Alad V went as far as using the Virus on his own body and sacrificing prototypes from his Zanuka Project.

After being defeated a second time and purging his body of the Infestation, Alad V had served as an unlikely ally of the Lotus and the Tenno, even attracting the hatred of the Stalker and his allies in the process.

He recently returned to the Corpus, though his miscomings lowered his reputation significantly. To makeup for his faults, Alad V entered an unlikely partnership with Sentients and begun a new project in Amalgams, transforming Grineer and Corpus soldiers into hybridized Sentients.

Alad V is first encountered on Themisto, Jupiter as a Corpus boss, where he is accompanied by his robotic pet and guardian, Zanuka, which he built from Warframe parts that he gathered. Upon completion of this assassination mission, the player will receive Valkyr component blueprints.

Main article: Raptors

The Raptors are Corpus Bosses found in the Europa system, and are the only Corpus bosses capable of flight. They are all, in effect, extremely powerful Ospreys, with each boasting high defenses and damage output. Fighting them requires both mobility and cover to avoid their highly damaging attacks. All three models possess heavy armor on their backs but vulnerable underbellies and engines. They can be found in the Naamah mission node on Europa. After defeating them and finishing the mission, players will receive either the Nova Chassis, Neuroptics, or Systems blueprint. Upon death, the Raptors have a chance of dropping Morphics, Control Modules, or Neural Sensors.

Main article: Hyena Pack

The Hyena Pack are the final bosses of Neptune, made up by four unique and deadly variants of the Hyena proxy. They work in packs of up to four with each of them possessing a unique set of abilities. Each Hyena possesses a plasma repeater, and they are far more agile than any other enemy (other than the Grineer Manic) in the game, including Zanuka and Zanuka Hunter. Alongside their agility, they can also jump on to and cling to walls, though they cannot wallrun. The Lotus has marked them for assassination due to their extreme danger and destroying the models may slow down further production.

They can be found on the mission Psamathe on Neptune, and after defeating them and finishing the mission, the player will receive Loki component blueprints. They can also be found during Razorback Armada missions, and a completely different set of Hyena proxies exist on the Orb Vallis. Upon death, all the Hyenas have a chance of dropping Orokin Cells or Control Modules.

Main article: Ambulas

Ambulas is a cutting-edge Corpus combat proxy, manufactured at Hades and serving as boss of the Pluto system. Apart from being heavily armed, its most dangerous feature is its connection to the Animo AI processor, which allows it to learn on its own whenever it is defeated in combat, ensuring that Ambulas proxies cannot be defeated by the same strategy twice.

Ergo Glast, who is responsible for the Animo processor's creation during his time with the Corpus, tasks the Tenno with tracking down and destroying the Ambulas manufacturing plant in order to prevent a repetition of the catastrophe which occurred when the Orokin made similar strides with advanced AI.

After defeating it on the Boss node Hades and finishing the mission, the player will receive a  Trinity component blueprint. Upon death, Ambulas has a chance of dropping Morphics as well.

Main article: Razorback

The Razorback is a Corpus proxy introduced in the Divine Will Tactical Alert in Hotfix 18.4.10. The latest creation of Nef Anyo, who boastfully claims that it is "impervious to evil", has one weakness: it is not immune to the attacks of Anyo's previous creations, the Bursas.

Main article: Phorid

Phorid is an Infested Boss only found when an Invasion takes over the Assassination mission of a Planet. After players defeat it and reach the extraction point, they will receive either a Nyx Neuroptics, Chassis, or Systems blueprint upon mission completion. Upon death, Phorid has a chance of dropping rare resources of the planet it appears on.

Main article: Lephantis

Lephantis is a massive, multi-headed Infested boss introduced in Update 10.0. It is found in the Assassination mission located in the Orokin Derelict. To fight Lephantis, the player must craft a Derelict Assassination key, which requires five Lephantis Nav Coordinates. These special Nav Coordinates can only be obtained from Derelict missions. Defeating Lephantis will reward the player with a blueprint for the Neuroptics, Systems, or Chassis of the Nekros Warframe upon mission completion.

Main article: Juggernaut Behemoth

The Juggernaut Behemoth is the larger, boss variant of the Infested Juggernaut enemy.

It is a massive quadruped Infested creature, armed with formidable ranged attacks and deadly close-quarters combat abilities, which combined with its heavy armor makes it an intimidating opponent. Initially introduced in the Black Seed Scourge Tactical Alert, it can now be found in the last mission of The Jordas Precept, as well as the first portion of the Jordas Golem assassination mission.

Main article: Jordas Golem

The Jordas Golem, also known as J3-Golem, is the Infested Boss of Eris. An amalgamation of Infested flesh merged with Corpus ship technology and a reprogrammed Cephalon, the massive Jordas Golem uses powerful weapons combined with its formidable armor to combat enemies in deep space.

The Jordas Golem is found in its own Assassination node on Eris after a player has completed the Jordas Precept Quest. After defeating them and finishing the mission, the player receives either Atlas Neuroptics, Chassis or Systems blueprint.

Main article: Mutalist Alad V

Controlled by the Infestation and corrupted with its power, Mutalist Alad V is one of the two bosses of Eris, introduced in Update 15.5. To fight him, players need to craft the Mutalist Alad V Assassinate Key with the blueprint awarded from completing the Patient Zero quest. Only the player starting the mission will lose a key, similarly to Orokin Derelict keys.

Main article: Hemocyte

The Hemocyte is a gigantic Infested creature that can be encountered during Operation: Plague Star. It is summoned using an Infested Catalyst during the toxin mixing phase and drops the Hunter Set Mods.

Main article: Zealoid Prelate

The Zealoid Prelate is an Infested Boss introduced during the fifth episode of Nightwave: Series 2 – The Emissary. It wields the Pathocyst Infested Glaive and, upon death, it drops one of the Pathocyst components.

Main article: Ropalolyst

The Ropalolyst, or commonly referred to by the community and the developers as Flying Eidolon, Flydolon or Rolypoly, is a gigantic bird-like Sentient boss capable of flight. It can be found in the Remastered Corpus Gas City on its own Assassination node on Jupiter, requiring players to have completed Chimera Prologue to battle it. It was dispatched by the Sentients to ensure Alad V does not double-cross their "partnership", much to his displeasure. After defeating the Ropalolyst, the player will receive Wisp component blueprints.

Main article: Ven'kra Tel

Ven'kra Tel is a special Grineer Field Boss unit encountered in Orokin Sabotage missions where Grineer are the dominant enemy, who is one of the two units who guard the Void Key necessary to close the Void Portal. She possesses a blue jet pack identical to that used by Hellions that grants her excellent mobility, and can use her Vulkar and other ranged special abilities to engage Tenno from afar. Ven'kra Tel is always seen with her sister, mini-boss Sprag.

Main article: Sprag

Sprag is a Grineer Field Boss encountered during Orokin Sabotage missions where Grineer are the dominant enemy. She is one of the two units who guard the Void Key necessary to close the Void Portal. She possesses a jet pack identical to that used by Hellions that grants her excellent mobility, and can use her Manticore Axe and other special melee abilities to engage Tenno in close combat. Sprag is always seen with her sister mini-boss, Ven'kra Tel.

Main article: Lynx

The Lynx is a Field Boss that is encountered in an Orokin Sabotage (Marduk) that feature Corpus enemies, acting as the main miniboss from which the mission's Void Key drops. A (presumably stolen and re-programmed) Lynx can also appear as an active miniboss in one of the Grineer Spy mission tiles as a room centerpiece; the Lynx will activate if the player has been spotted/tripped the alarm before hacking the data vaults. It resembles a smaller Jackal with blue armor, and has the ability to deploy Osprey drones and Turrets to assist it in combat.

Main article: Juggernaut

The Juggernaut is a large, quadrupedal Infested creature armed with formidable ranged attacks and deadly close-quarters combat abilities. Combining these threats with its heavy armor shell, the Juggernaut becomes an intimidating opponent. The Juggernaut's abilities include a charging body attack, a ranged spine strike (a scaled version of the Phorid's similar attack) and the ability to resurrect a number of nearby dead Infested.

Main article: Corrupted Vor

Corrupted Vor is corrupted Captain Vor and is the boss of the Orokin Void as an encounter in the high level Void missions (Level ≥40). It is known that he was revived by his own Orokin Key sometime after his defeat and has since turned into the guardian of the Void. Vor will make his presence known via a taunting transmission, after which he will appear near players to engage them in battle.

Main article: Leekter

Leekter is a member of The Grustrag Three. He wields a Manticore axe and throws flashbangs to blind players in battle.

Although Leekter does not spawn by himself under normal circumstances, he may individually spawn inside Darvo's weekly mission as a Field Boss if the associated faction of the mission are Grineer.

Main article: Shik Tal

Shik Tal is a member of The Grustrag Three. He wields a modified  Marelok that fires small dumb-fire rockets (akin to those fired by Hellions) and a giant shield similar to Shield Lancers. Similar to the Shield Lancers themselves, he can use his shield to charge forward to knockdown and knockback players.

Although Shik Tal does not spawn by himself under normal circumstances, he may individually spawn inside Darvo's weekly mission as a Field Boss if the associated faction of the mission are Grineer.

Main article: Vem Tabook

Vem Tabook is the leader of The Grustrag Three. He uses a modified  Hek that fires electro-shells in bursts of around 10 at its target, each shell dealing electricity damage in a small radius, making them deadly should all of them connect with their target or the surrounding terrain.

Although Vem Tabook does not spawn by himself under normal circumstances, he may individually spawn inside Darvo's weekly mission as a Field Boss if the associated faction of the mission are Grineer.

Main article: John Prodman

John Prodman is a rarely-encountered enemy in The Index. Similar to Clem, Prodman has his roots as a meme within the WARFRAME community.

According to the description of his autograph, he is an employee of Anyo Corp, and was recently awarded "Employee of the Month".

Main article: Kuva Lich

Main article: Angst

Angst is one of Shadow Stalker's acolytes, first appearing in Operation: Shadow Debt. She takes the form of a Valkyr Warframe with an Immortal Skin, wearing Stalker's helmet and the Vanquished Syandana.

Main article: Malice

Malice is one of Shadow Stalker's acolytes. He takes the form of Frost with a Prime Skin, minus his signature shoulder armor, with Stalker's helmet and large chunks of machinery around his body.

Main article: Mania

Mania is one of Shadow Stalker's acolytes. He takes the form of Loki with an Immortal Skin, wearing Stalker's helmet and a Daedalus Shoulder Plate.

Main article: Torment

Torment is one of Shadow Stalker's Acolytes. She takes the form of Mesa with Stalker's helmet, a Naberus shoulder piece, and some of Equinox's front tassels. She also uses an Eos chest plate for a codpiece, and the Eos spurs.

Main article: Violence

Violence is one of Shadow Stalker's acolytes. He takes the form of Limbo wearing Stalker's helmet and the pieces from the Hulta armor set.

Main article: Stalker

The Stalker is an ominous, vengeful figure that infrequently appears during missions, armed with powerful weapons and abilities to hunt down Tenno who have his Death Mark.

The Stalker wears Warframe armor and is able to use ability powers belonging to various other Warframes. His arsenal is similar to that of the Tenno, utilizing a primary, secondary, and melee weapon. The Stalker's signature weapons are the bow Dread, the scythe Hate, and the throwing knives Despair.

If the Tenno marked for assassination has completed The Second Dream quest, they will be confronted with the more powerful, Sentient-enhanced Shadow Stalker instead.

Main article: Shadow Stalker

The Shadow Stalker is an ominous, vengeful figure that infrequently appears during missions, armed with the War and powerful abilities to hunt down the Tenno. He appears during and after The Second Dream quest. Visually, the Shadow Stalker takes the form of a modified Excalibur with his own original helmet, and donning the Sentient-imbued Pakal Armor Set.

As seen in the aforementioned quest, the Shadow Stalker was gifted with Sentient powers and equipment by Hunhow, allowing him to adapt to damage continuously as well as releasing new forms of power. This appears to have cost him some of his previous abilities such as Absorb and Shuriken.

He can only be fought if the Tenno has confronted him during The Second Dream; if the Tenno in question has not, they will be confronted with the pre-Second Dream Stalker instead.

Main article: Zanuka Hunter

The Zanuka Hunter, formerly known as the Harvester, is a gray-colored Zanuka proxy controlled by Alad V. During missions, it will attack one targeted Tenno until either the Tenno or Zanuka Hunter dies. It appears rarely, in a manner similar to the Stalker. Triggering a Zanuka Hunter attack requires a player to have a Death Mark, acquired by fighting against the Corpus across five Invasion missions, or it can be summoned by using a Zanuka Hunter Beacon.

Main article: The Grustrag Three

The Grustrag Three (commonly abbreviated as the G3) are a group of Assassins, founded by Councilor Vay Hek, who come after Tenno that have completed five consecutive Invasion missions against the Grineer.

Main article: Wolf of Saturn Six

The Wolf of Saturn Six is a rogue Grineer criminal introduced as an antagonist in Nightwave: Series 1 – The Wolf of Saturn Six. Formerly a model prisoner of the previously undisclosed Saturn Six penitentiary, the Wolf escaped along with his "pack" of Saturn Six Fugitives. He later underwent Sentient hybridizing after being enslaved by Alad V and sent to hunt down the Tenno. He eventually broke free once again, and disappeared alongside his comrades.

During Nightwave: Series 1, the Wolf could spawn randomly in almost any player-accessible mission, similar to Assassins but without the Death Mark. For the entire length of the Series, all players could be considered to have a permanent death mark. As Series 1 escalated, his spawn chances also increased incrementally.

Towards the end of Series 1, a Tactical Alert was issued to hunt down the Wolf in two Assassination-type missions of varying levels, with double the chance to drop Wolf Sledge components on the higher level mission (35% vs 70%).

Following the end of Nightwave: Series 1, Wolf Beacons can be bought from Nightwave Cred Offerings to forcibly draw out the Wolf.

Main article: Eidolon Teralyst

The Eidolon Teralyst is a gigantic spectral Sentient Eidolon creature that can be found aimlessly roaming around the Plains of Eidolon at night, acting as one of the Grand Bosses of the landscape.

The Eidolons are remnants of a massive Sentient that was defeated in a battle against the Tenno during the Old War, whose remains now wander the plains perpetually searching for their lost components. These fragments are, however, still formidable creatures armed with powerful attacks and near-impenetrable defenses, and are hostile to both Tenno and Grineer alike.

It is important to note players that have not unlocked Transference from The War Within won't have any means to properly fight the Eidolon Teralyst.

Main article: Eidolon Gantulyst

The Eidolon Gantulyst is an enormous spectral Sentient Eidolon creature that can be summoned on the Plains of Eidolon at night, acting as one of the Grand Bosses of the landscape. Much larger than the more common Teralyst Eidolon, it has replaced its right arm with an elongated boulder, and its massive weight creates shockwaves with every step.

All Eidolons are remnants of a Sentient that was defeated in a battle against the Tenno during the Old War, whose remains now wander the plains perpetually searching for their lost components. These fragments are, however, still formidable creatures armed with powerful attacks and near-impenetrable defenses, and are hostile to both Tenno and Grineer alike.

It is important to note players that have not unlocked Transference from The War Within won't have any means to properly fight the Eidolon Gantulyst.

Main article: Eidolon Hydrolyst

The Eidolon Hydrolyst is a titanic spectral Sentient Eidolon creature that can be summoned on the Plains of Eidolon at night, acting as one of the Grand Bosses of the landscape. It is large enough to wield the landing strut of an ancient spacecraft as a weapon, and its arcane energies create localized storm systems wherever it surfaces.

All Eidolons are remnants of a Sentient that was defeated in a battle against the Tenno during the Old War, whose remains now wander the plains perpetually searching for their lost components. These fragments are, however, still formidable creatures armed with powerful attacks and near-impenetrable defenses, and are hostile to both Tenno and Grineer alike.

It is important to note players that have not unlocked Transference from The War Within won't have any means to properly fight the Eidolon Hydrolyst.

Main article: Profit-Taker Orb

Profit-Taker Orb is a large Raknoid creature found in Enrichment Labs in the Orb Vallis on top of the building, acting as one of the Grand Bosses of the landscape. The gargantuan creature can only be engaged during the Heist with Vox Solaris, requiring the rank of Old Mate within Solaris United.

The orb incorporates Sentient technology within its shields (which is put into overcharge by satellites) and is protected by an extremely durable carapace, making it seemingly invulnerable.

Main article: Exploiter Orb

Exploiter Orb is a large Raknoid creature that can be found patrolling around the Temple of Profit within the Orb Vallis, acting as one of the Grand Bosses of the landscape. She is the one responsible for the destruction of Deck 12 which left many of its Solaris United survivors traumatized. The Exploiter Orb is battled in the ruins of Deck 12 located in a cave northeast of Harindi Crater, requiring a single Diluted Thermia from the recurring Thermia Fractures event.

Unlike the Profit-Taker Orb, the Exploiter Orb lacks Sentient adaptive shielding, but her carapace remains impervious to all gunfire. To defend herself, the Exploiter Orb can surround herself with a winter storm on command and has four vents across her lower body which spray jets of ice and an underbelly turret. Her main weakness of overheating is kept in check by her numerous exhaust vents as well as the small squad of Coolant Raknoids accompanying her.

Main article: Arn Etina

Arn Etina was once the name of the final boss of Pluto, a black MOA found on Hades. Upon death there was a chance he would drop one of the components required to build Excalibur. Arn Etina's name was changed to Ambulas as of Update 6.0.

Despite being a MOA, Arn Etina used a human-like game picture for their transmissions. The game picture and appearance have since been repurposed for Darvo.

Main article: J3-Golem