Each Warframe has a different style of play and a different set of stats and abilities, or Attributes, that make them unique from other Warframes.
- Main article: Health
Health represents how much damage a Warframe can sustain before becoming incapacitated or killed. Health is indicated as a red numeric value at the top right of the screen. While a Warframe loses Health, the screen's edges will begin to pulse red. Once the Warframe reaches 10% health or below, a loud, heartbeat-like sound will begin to play, and a slight ringing can be heard. This sound also plays when dead and when incapacitated.
- Main article: Death
Upon reaching zero health, Warframes will go into bleedout, which is a twenty-second period of dramatically-reduced combat capability, collapsing onto the ground and only being able to use secondary weapons. If the Warframe is not revived during this time, it dies a proper death and must either spend 10% of their Affinity acquired during the mission to continue playing the mission, wait for an ally to finish the mission, or forfeit the mission entirely. Players are only allowed to revive 4 times per mission, barring special circumstances.
- Main article: Shield
Shields are invisible barriers that absorb incoming damage and protects the player from taking Health damage against enemy attacks. Unlike health, shields regenerate after three seconds of not taking damage, making them a naturally replenishing defense.
- Main article: Shield#Overshield
Overshields are extra shield points on top of the normal maximum shielding, which are acquired through the use of active shield restoration items or abilities that would restore shields beyond the Warframe's maximum shield capacity. The player's shield counter changes from blue to purple while possessing overshields.
- Main article: Armor
Armor mitigates a percent of incoming damage. Armor only reduces damage applied to a Warframe's Health and does not affect damage absorbed by its Shields.
- Main article: Energy Capacity
Energy of a Warframe is used mainly to power abilities and melee channeling. All Warframes have 4 abilities that at base, cost up to 100 energy to cast. Every Warframe has their own energy-pool with varying capacities depending on the types and costs of their various abilities.
- Main article: Sprint Speed