Talk:Enemy Vulnerabilities/@comment-92.80.50.113-20130918165437/@comment-11753608-20130918173533

The only multiplier for Freeze damage is x2 to shields. This would arguably make it most effective against Corpus. However, research done prior to U10 suggested that Freeze damage was not always first to be calculated against shields, which makes this a complicated issue. While this may no longer be the case since they may have done some updates to the damage system, it seems to me that Freeze damage is best used against high level heavy mobs or bosses for the Grineer and Corpus factions. That said, when you get to the point that your weapons are already modded pretty high, you are going to end up putting freeze on there anyway. Also keep in mind that Freeze damage also has the most effective secondary effect (slows time scale) that is best used against Infested or melee mobs. So there are reasons to keep it on your weapons for every faction.