Talk:Hildryn/@comment-172.58.27.54-20200214002116/@comment-170.249.153.179-20200216125857

Yet said "infection" is stated to have such effects as hardening skin into "sword-flesh" and hard-packing organs together for greater durability, which is kinda counter-intuitive for reproductive purposes.

Plus most such augmented soldiers in media (40k space marines for example) tend to have their reproductive drive/ability erased so no biological urges will distract them from their intended purpose of being biological weapons.

So unless you count such abilities as Nidus's maggot spawns or expect DE would go the route of having some sufficiently rich and sufficiently perverted Orokin commission himself a Warframe bodyguard/concubine as a canon possibility, I'd say the odds of Frames being able to reproduce are slim.